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MITRE ATT&CK® Malware

S0583: Pysa

Pysa is a ransomware that was first used in October 2018 and has been seen to target particularly high-value finance, government and healthcare organizations.[1]

EnterpriseS0583MalwareObject v1.0Modified
Glexia's Take · Automated analysis

Security context for executives and security teams

Automation confidenceMedium

S0583: Pysa describes [Pysa](https://attack.mitre.org/software/S0583) is a ransomware that was first used in October 2018 and has been seen to target particularly high-value finance, government and healthcare organizations.(Citation: CERT-FR PYSA April 2020)

Executive priority

S0583: Pysa is an official MITRE ATT&CK software. Glexia treats it as defensive behavior context for prioritizing monitoring, control validation, and response planning without using the object by itself as an attribution claim.

Technical view

Security teams should validate S0583: Pysa by reviewing the official ATT&CK relationships, mapped tactics (the mapped ATT&CK tactic context), supported platforms (Windows), and available local telemetry before making detection or mitigation decisions.

Likely telemetry

  • Official ATT&CK relationships and object metadata
  • Network, endpoint, and security-tool telemetry

Detection direction

  • Validate whether S0583: Pysa appears in your detection coverage and tabletop scenarios.
  • Use the object to align executive risk language with SOC, incident response, and detection engineering work.
  • Do not treat ATT&CK relationship context as attribution without corroborating evidence.

Mitigation priorities

  • Map the object to existing controls and identify missing telemetry or response ownership.
  • Prioritize mitigations that reduce exposure on the listed platforms and tactics.
  • Review adjacent ATT&CK relationships before changing policy, detections, or reporting language.
Additional notes and limits

Baseline Glexia take generated from the official MITRE ATT&CK STIX object, source hash, tactics, platforms, and detection fields. It is safe to replace with a richer model-generated take for the same source hash later.

This baseline take is source-grounded and schema-validated, but it does not include environment-specific telemetry, incident evidence, or threat-intelligence corroboration.

Generated from the cited source records. This long-tail analysis has not been individually reviewed by a named human.

Official MITRE ATT&CK definition

Pysa

Pysa is a ransomware that was first used in October 2018 and has been seen to target particularly high-value finance, government and healthcare organizations.[1]

View the same entry on attack.mitre.org (MITRE-hosted reference; in-page links above use the Glexia ATT&CK library.)

Glexia analysis

How security teams should use this page

Treat this object as behavior context, not an attribution claim. Validate the related groups, software, data sources, and mitigations against official ATT&CK relationships and your own telemetry before making control-coverage decisions.

ATT&CK relationship table

Techniques used

This mirrors the MITRE pattern of making group, software, campaign, and technique relationships scannable. Relationship notes come from mirrored ATT&CK relationship text when available.

16 rows
DomainIDNameRelationship / procedure
EnterpriseT1016System Network Configuration Discovery

Pysa can perform network reconnaissance using the Advanced IP Scanner tool.[1]

EnterpriseT1059.006PythonSub-technique

Pysa has used Python scripts to deploy ransomware.[1]

EnterpriseT1552.001Credentials In FilesSub-technique

Pysa has extracted credentials from the password database before encrypting the files.[1]

EnterpriseT1685Disable or Modify Tools

Pysa has the capability to stop antivirus services and disable Windows Defender.[1]

EnterpriseT1059.001PowerShellSub-technique

Pysa has used Powershell scripts to deploy its ransomware.[1]

EnterpriseT1486Data Encrypted for Impact

Pysa has used RSA and AES-CBC encryption algorithm to encrypt a list of targeted file extensions.[1]

EnterpriseT1112Modify Registry

Pysa has modified the registry key “SOFTWARE\Microsoft\Windows\CurrentVersion\Policies\System” and added the ransom note.[1]

EnterpriseT1021.001Remote Desktop ProtocolSub-technique

Pysa has laterally moved using RDP connections.[1]

EnterpriseT1569.002Service ExecutionSub-technique

Pysa has used PsExec to copy and execute the ransomware.[1]

EnterpriseT1003.001LSASS MemorySub-technique

Pysa can perform OS credential dumping using Mimikatz.[1]

EnterpriseT1489Service Stop

Pysa can stop services and processes.[1]

EnterpriseT1490Inhibit System Recovery

Pysa has the functionality to delete shadow copies.[1]

EnterpriseT1036.005Match Legitimate Resource Name or LocationSub-technique

Pysa has executed a malicious executable by naming it svchost.exe.[1]

EnterpriseT1110Brute Force

Pysa has used brute force attempts against a central management console, as well as some Active Directory accounts.[1]

EnterpriseT1070.004File DeletionSub-technique

Pysa has deleted batch files after execution. [1]

EnterpriseT1046Network Service Discovery

Pysa can perform network reconnaissance using the Advanced Port Scanner tool.[1]

Relationship explorer

All related ATT&CK context

Change history

Object version and sync metadata

The fields below describe the current mirrored snapshot. When Glexia retains multiple ATT&CK source imports, you can open the table to compare the same object across releases (hashes and MITRE timestamps). For MITRE’s own release notes and roadmap, see ATT&CK resources — Updates.

ATT&CK release
19.2
Object version
1.0
Created
Modified
Raw hash
1d1d5fc995263a57...
Imported snapshots across ATT&CK releases(2)
ReleaseBundle importedObject versionModifiedStatusRaw hash
19.21.0Current bundle1d1d5fc99526…
19.11.0Older bundle1d1d5fc99526…
Raw source

Mirrored ATT&CK source object

The raw object is retained through the mirrored ATT&CK source bundle and object hash. The raw endpoint returns the exact object from the mirrored bundle when available.

Source references

External references and citations

MITRE external references are preserved separately from Glexia analysis so citations remain traceable to their original source records.

  1. [1]
    CERT-FR PYSA April 2020

    CERT-FR. (2020, April 1). ATTACKS INVOLVING THE MESPINOZA/PYSA RANSOMWARE. Retrieved March 1, 2021.

    Open source URL
  2. [2]
    DFIR Pysa Nov 2020

    THe DFIR Report. (2020, November 23). PYSA/Mespinoza Ransomware. Retrieved March 17, 2021.

    Open source URL
  3. [3]
    Mespinoza

    (Citation: CERT-FR PYSA April 2020)(Citation: DFIR Pysa Nov 2020)(Citation: NHS Digital Pysa Oct 2020)

  4. [4]
    NHS Digital Pysa Oct 2020

    NHS Digital. (2020, October 10). Pysa Ransomware: Another 'big-game hunter' ransomware. Retrieved March 17, 2021.

    Open source URL
  5. [5]
    Pysa

    (Citation: CERT-FR PYSA April 2020)(Citation: DFIR Pysa Nov 2020)(Citation: NHS Digital Pysa Oct 2020)

  6. [6]
    mitre-attackS0583
    Open source URL
Source and licensing

Source: MITRE ATT&CK®. © 2026 The MITRE Corporation. This work is reproduced and distributed with the permission of The MITRE Corporation. MITRE ATT&CK and ATT&CK are registered trademarks of The MITRE Corporation. Glexia is not affiliated with or endorsed by MITRE.