Security readout for executives and security teams
Plain-English summary
CVE-2025-21365 is a high-severity Microsoft Office remote code execution issue. Affected Office users may be at risk if user interaction occurs. Microsoft has published advisory and patch information, so this should be handled as a normal priority enterprise Office update, not deferred.
Executive priority
Treat as high priority for endpoint patching because Office is widely deployed and impact is full system compromise if exploitation succeeds. Current evidence does not show known active exploitation in the provided sources.
Technical view
The provided record describes a Microsoft Office RCE with CVSS 7.8, CWE-426, local attack vector, low complexity, no privileges required, and required user interaction. Impact is high for confidentiality, integrity, and availability. Affected products listed are Microsoft 365 Apps for Enterprise 16.0.1 and Microsoft Office LTSC 2024 16.0.0.
Likely exposure
Organizations running the listed Microsoft Office products or versions may be exposed, especially on endpoints where Office documents are opened by users. Exposure should be validated against Microsoft inventory, update channels, and installed build data.
Exploitation context
The provided data does not support active exploitation: KEV is false and CVSS exploit maturity is unproven. User interaction is required, and the attack vector is listed as local. No exploit details are included in the sources.
Researcher notes
Key constraints are CVSS AV:L and UI:R despite the RCE title. CWE-426 suggests search path behavior, but the bundle does not provide mechanics. Do not infer affected versions, exploitability, or mitigations beyond Microsoft guidance.
Mitigation direction
- Apply Microsoft updates referenced by MSRC for CVE-2025-21365.
- Prioritize affected Office endpoints in enterprise patch management.
- Check Microsoft guidance for supported update channels and fixed builds.
- Use standard document-handling controls until affected endpoints are updated.
Validation and detection
- Inventory Microsoft 365 Apps for Enterprise and Office LTSC 2024 installations.
- Compare installed Office versions with Microsoft advisory guidance.
- Confirm endpoints receive the relevant Microsoft Office security update.
- Review vulnerability scanner findings against the MSRC CVE record.
Public sources used
Generated from the cited source records. This long-tail analysis has not been individually reviewed by a named human.
Conservative CVE-to-ATT&CK context
These mappings and lookup hints may be relevant to the vulnerability behavior, CWE, affected product, or exposure path. Glexia-inferred context is not an official MITRE, ATT&CK, CWE, or CVE Program mapping.
ATT&CK lookup starting points
Use these exact CWE pages and searches to review the Glexia ATT&CK library from this CVE's weakness and description context.
CWE-426: Exact CWE lookup
Use the exact CWE identifier as the starting point before reviewing related ATT&CK behavior. Open the exact CWE lookup page first, then review the ATT&CK searches from that MITRE weakness context. This is a Glexia lookup hint, not an official ATT&CK mapping.
Open ATT&CK lookupExecution behavior lookup
The CVE wording references code or command execution, so execution technique review may help defensive triage. This is a Glexia inferred lookup path, not an official MITRE, ATT&CK, or CVE Program mapping.
Open ATT&CK lookupCVE-2025-21365 mapping review
Open the CVE-to-ATT&CK bridge for reviewed, inferred, or future official mappings tied to this CVE.
Open ATT&CK lookup- Severity
- High
- CVSS
- 7.8 (3.1)
- Known Exploited
- No
- Published
Vector: CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:C
CNA and ADP enrichment extracted from CVE v5
These fields come from the CVE record and ADP containers, not from Glexia's Take. They preserve time-varying source decisions such as CISA SSVC, KEV status, CVSS metrics, and provider references.
SSVC decision data
CVSS vector scores
1 official scoreWe collect every scored CVSS vector available in the official CNA and ADP containers. When more than one version is present, the table keeps the source vectors side by side instead of collapsing them into the highest score.
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:C1.85.9microsoftVulnerability scoring details
Base CVSS 3.1 score
7.8HighVector: CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H/E:U/RL:O/RC:C
Vulnerability timeline
Timeline events are normalized from CVE metadata, CNA source timelines, ADP timelines, and KEV metadata when present.
- CVE reservedCVE Program
The CVE ID was reserved by the assigning CNA.
- CVE publishedCVE Program
The CVE record was published.
- CVE updatedCVE Program
The CVE record metadata indicates this as the latest update time.
ADP provider summaries
Source materials
- CVE List V5 sourceCVE List V5
- Microsoft Office Remote Code Execution VulnerabilityCVE reference, microsoft · vendor-advisory, patch
Products and packages named in the record
CWE details
CWE links open Glexia weakness intelligence pages with official CWE context, developer remediation guidance, and related CVE mappings.
Untrusted Search Path
Untrusted Search Path represents a recurring weakness pattern that can create exploitable paths when design, validation, or implementation controls are missing.