LiveActive security incident?Get immediate response
CVE Record

CVE-2022-46294: Multiple out-of-bounds write vulnerabilities exist in the translationVectors parsing functionality in multi...

Multiple out-of-bounds write vulnerabilities exist in the translationVectors parsing functionality in multiple supported formats of Open Babel 3.1.1 and master commit 530dbfa3. A specially-crafted malformed file can lead to arbitrary code execution. An attacker can provide a malicious file to trigger this vulnerability.This vulnerability affects the MOPAC Cartesian file format

CriticalCVSS 9.8Not KEV-listedUpdated
Glexia's TakeAutomated analysiscritical

Security readout for executives and security teams

Plain-English summary

Open Babel can be made to corrupt memory while reading a malformed MOPAC Cartesian chemical file. If an exposed service automatically processes files with vulnerable Open Babel versions, this could allow arbitrary code execution in that service context.

Executive priority

Treat as urgent for internet-facing or partner-facing file ingestion services using Open Babel. The business risk is service compromise through a file parser, but evidence of active exploitation is not provided in the source bundle.

Technical view

CVE-2022-46294 is a CWE-119 out-of-bounds write in Open Babel translationVectors parsing. Sources name Open Babel 3.1.1 and master commit 530dbfa3, specifically affecting the MOPAC Cartesian format. Talos reports specially crafted malformed files can lead to arbitrary code execution.

Likely exposure

Highest exposure is in web applications, APIs, batch pipelines, or research platforms that accept molecular structure files and pass them to Open Babel. Local desktop use is lower urgency unless users open untrusted files.

Exploitation context

The source bundle does not show CISA KEV listing or public active exploitation evidence. The reported path is attacker-supplied malicious file content processed by vulnerable Open Babel parsing logic.

Researcher notes

The evidence identifies affected versions and impact, but the bundle does not include a fixed version, patch commit, or active exploitation report. Avoid assuming exploit availability beyond Talos' statement that crafted malformed files can trigger the issue.

Mitigation direction

  • Identify and prioritize systems using Open Babel 3.1.1 or commit 530dbfa3.
  • Check Open Babel and Talos guidance for patched versions or vendor-recommended remediation.
  • Restrict or disable untrusted MOPAC Cartesian file processing where operationally possible.
  • Run file conversion workloads with least privilege and process isolation.
  • Limit upload sources and add strict file handling around molecular conversion services.

Validation and detection

  • Inventory applications, containers, and pipelines that include Open Babel.
  • Confirm whether MOPAC Cartesian files are accepted or auto-processed.
  • Trace public upload paths, APIs, and queues feeding Open Babel conversion.
  • Review vendor release notes for fixed versions before declaring remediation complete.
  • Check conversion service logs for unexplained crashes during malformed file handling.
Prepared
Confidence
high
Sources
3

Generated from the cited source records. This long-tail analysis has not been individually reviewed by a named human.

Potential ATT&CK relevance

Conservative CVE-to-ATT&CK context

These mappings and lookup hints may be relevant to the vulnerability behavior, CWE, affected product, or exposure path. Glexia-inferred context is not an official MITRE, ATT&CK, CWE, or CVE Program mapping.

ATT&CK lookup starting points

Use these exact CWE pages and searches to review the Glexia ATT&CK library from this CVE's weakness and description context.

cwe · low confidence lookup

CWE-119: Exact CWE lookup

Use the exact CWE identifier as the starting point before reviewing related ATT&CK behavior. Open the exact CWE lookup page first, then review the ATT&CK searches from that MITRE weakness context. This is a Glexia lookup hint, not an official ATT&CK mapping.

Open ATT&CK lookup
description · low confidence lookup

Execution behavior lookup

The CVE wording references code or command execution, so execution technique review may help defensive triage. This is a Glexia inferred lookup path, not an official MITRE, ATT&CK, or CVE Program mapping.

Open ATT&CK lookup
cve · low confidence lookup

CVE-2022-46294 mapping review

Open the CVE-to-ATT&CK bridge for reviewed, inferred, or future official mappings tied to this CVE.

Open ATT&CK lookup
Vulnerability profileCVE Program record
Severity
Critical
CVSS
9.8 (3.1)
Known Exploited
No
Published

Vector: CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H

Official CVE source material

CNA and ADP enrichment extracted from CVE v5

These fields come from the CVE record and ADP containers, not from Glexia's Take. They preserve time-varying source decisions such as CISA SSVC, KEV status, CVSS metrics, and provider references.

1CVSS vectors
0Timeline events
0ADP providers
3Source links

CVSS vector scores

1 official score

We collect every scored CVSS vector available in the official CNA and ADP containers. When more than one version is present, the table keeps the source vectors side by side instead of collapsing them into the highest score.

ScoreVersionSeverityVectorExploitImpactSource
9.8CVSS 3.1CriticalCVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H3.95.9Primary CVE score

Vulnerability scoring details

Base CVSS 3.1 score

9.8Critical
CVSS 3.1 vector shape for CVE-2022-46294Attack VectorAttack ComplexityPrivileges RequiredUser InteractionScopeConfidentiality ImpactIntegrity ImpactAvailability Impact

Vector: CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H

Attack Vector
NetworkAdjacentLocalPhysical
Attack Complexity
LowHigh
Privileges Required
NoneLowHigh
User Interaction
NoneRequired
Scope
ChangedUnchanged
Confidentiality Impact
HighLowNone
Integrity Impact
HighLowNone
Availability Impact
HighLowNone
Affected products

Products and packages named in the record

VendorProductVersion / packageStatus
Open BabelOpen Babel3.1.1, master commit 530dbfa3Listed
Weakness

CWE details

CWE links open Glexia weakness intelligence pages with official CWE context, developer remediation guidance, and related CVE mappings.

CWE-119 · source CWE mapping

Improper Restriction of Operations within the Bounds of a Memory Buffer

Improper Restriction of Operations within the Bounds of a Memory Buffer represents a recurring weakness pattern that can create exploitable paths when design, validation, or implementation controls are missing.