Security readout for executives and security teams
Plain-English summary
Open Babel can be crashed or potentially taken over when it processes a malicious PQS molecular file. The source states this can lead to arbitrary code execution in Open Babel 3.1.1 and one master commit. Treat systems that automatically process external chemistry files as high priority.
Executive priority
Prioritize remediation for internet-facing, shared, or automated file-processing environments. The business risk is highest where untrusted scientific files are parsed without isolation.
Technical view
The flaw is an out-of-bounds write in Open Babel's PQS format coord_file functionality. A specially crafted malformed file can trigger memory corruption and possible arbitrary code execution. The CVE lists Open Babel 3.1.1 and master commit 530dbfa3 as affected.
Likely exposure
Exposure is most likely where Open Babel processes PQS files from users, partners, email attachments, uploads, pipelines, or public datasets. The bundle does not identify downstream packaged products or hosted services.
Exploitation context
The CVE says an attacker can provide a malicious file to trigger the vulnerability. CISA KEV is not cited, and the provided bundle does not show active exploitation in the wild.
Researcher notes
Evidence is limited to the CVE bundle and Talos advisory reference. The reported impact is arbitrary code execution via malformed PQS parsing, but no exploit-in-the-wild evidence or specific fixed version is included here.
Mitigation direction
- Inventory Open Babel installations and confirm whether 3.1.1 or commit 530dbfa3 is present.
- Check Open Babel and Talos guidance for fixed versions or vendor-supported remediation.
- Temporarily avoid processing untrusted PQS files until remediation is confirmed.
- Isolate file conversion workflows with least privilege and constrained runtime access.
- Monitor CVE, Talos, and vendor advisories for updated remediation details.
Validation and detection
- Search servers, containers, CI images, and workstations for Open Babel binaries and libraries.
- Confirm whether applications accept or automatically process PQS files.
- Review upload, batch conversion, and research pipeline paths for untrusted file ingestion.
- Verify remediated systems no longer report affected Open Babel versions.
- Document compensating controls where upgrade status is pending.
Public sources used
Generated from the cited source records. This long-tail analysis has not been individually reviewed by a named human.
Conservative CVE-to-ATT&CK context
These mappings and lookup hints may be relevant to the vulnerability behavior, CWE, affected product, or exposure path. Glexia-inferred context is not an official MITRE, ATT&CK, CWE, or CVE Program mapping.
ATT&CK lookup starting points
Use these exact CWE pages and searches to review the Glexia ATT&CK library from this CVE's weakness and description context.
CWE-119: Exact CWE lookup
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Open ATT&CK lookupExecution behavior lookup
The CVE wording references code or command execution, so execution technique review may help defensive triage. This is a Glexia inferred lookup path, not an official MITRE, ATT&CK, or CVE Program mapping.
Open ATT&CK lookupCVE-2022-43467 mapping review
Open the CVE-to-ATT&CK bridge for reviewed, inferred, or future official mappings tied to this CVE.
Open ATT&CK lookup- Severity
- Critical
- CVSS
- 9.8 (3.1)
- Known Exploited
- No
- Published
Vector: CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H
CNA and ADP enrichment extracted from CVE v5
These fields come from the CVE record and ADP containers, not from Glexia's Take. They preserve time-varying source decisions such as CISA SSVC, KEV status, CVSS metrics, and provider references.
CVSS vector scores
1 official scoreWe collect every scored CVSS vector available in the official CNA and ADP containers. When more than one version is present, the table keeps the source vectors side by side instead of collapsing them into the highest score.
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H3.95.9Primary CVE scoreVulnerability scoring details
Base CVSS 3.1 score
9.8CriticalVector: CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H
Source materials
Products and packages named in the record
CWE details
CWE links open Glexia weakness intelligence pages with official CWE context, developer remediation guidance, and related CVE mappings.
Improper Restriction of Operations within the Bounds of a Memory Buffer
Improper Restriction of Operations within the Bounds of a Memory Buffer represents a recurring weakness pattern that can create exploitable paths when design, validation, or implementation controls are missing.
