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MITRE ATT&CK® Technique

T1546.018: Python Startup Hooks

Adversaries may achieve persistence by leveraging Python’s startup mechanisms, including path configuration (`.pth`) files and the `sitecustomize.py` or `usercustomize.py` modules. These files are automatically processed during the initialization of the Python interpreter, allowing for the execution of arbitrary code whenever Python is invoked.[1]

Path configuration files are designed to extend Python’s module search paths through the use of import statements. If a `.pth` file is placed in Python's `site-packages` or `dist-packages` directories, any lines beginning with `import` will be executed automatically on Python invocation.[2] Similarly, if `sitecustomize.py` or `usercustomize.py` is present in the Python path, these files will be imported during interpreter startup, and any code they contain will be executed.[3]

Adversaries may abuse these mechanisms to establish persistence on systems where Python is widely used (e.g., for automation or scripting in production environments).

EnterpriseT1546.018Sub-techniqueObject v1.0Modified
Glexia's Take · Automated analysis

Security context for executives and security teams

Automation confidenceMedium

T1546.018: Python Startup Hooks describes Adversaries may achieve persistence by leveraging Python’s startup mechanisms, including path configuration (`.pth`) files and the `sitecustomize.py` or `usercustomize.py` modules. These files are automatically processed during the initialization of the Python interpreter, allowing for the execution of arbitrary code whenever Python is invoked.(Citation: Volexity GlobalProtect CVE 2024) Path configuration files are designed to extend Python’s module search paths through the use of import statements. If a `.pth` fil...

Executive priority

T1546.018: Python Startup Hooks is an official MITRE ATT&CK technique. Glexia treats it as defensive behavior context for prioritizing monitoring, control validation, and response planning without using the object by itself as an attribution claim.

Technical view

Security teams should validate T1546.018: Python Startup Hooks by reviewing the official ATT&CK relationships, mapped tactics (persistence, privilege-escalation), supported platforms (Linux, macOS, Windows), and available local telemetry before making detection or mitigation decisions.

Likely telemetry

  • Official ATT&CK relationships and object metadata
  • Identity, privilege, and authentication events
  • Network, endpoint, and security-tool telemetry

Detection direction

  • Validate whether T1546.018: Python Startup Hooks appears in your detection coverage and tabletop scenarios.
  • Use the object to align executive risk language with SOC, incident response, and detection engineering work.
  • Do not treat ATT&CK relationship context as attribution without corroborating evidence.

Mitigation priorities

  • Map the object to existing controls and identify missing telemetry or response ownership.
  • Prioritize mitigations that reduce exposure on the listed platforms and tactics.
  • Review adjacent ATT&CK relationships before changing policy, detections, or reporting language.
Additional notes and limits

Baseline Glexia take generated from the official MITRE ATT&CK STIX object, source hash, tactics, platforms, and detection fields. It is safe to replace with a richer model-generated take for the same source hash later.

This baseline take is source-grounded and schema-validated, but it does not include environment-specific telemetry, incident evidence, or threat-intelligence corroboration.

Generated from the cited source records. This long-tail analysis has not been individually reviewed by a named human.

Official MITRE ATT&CK definition

Python Startup Hooks

Adversaries may achieve persistence by leveraging Python’s startup mechanisms, including path configuration (`.pth`) files and the `sitecustomize.py` or `usercustomize.py` modules. These files are automatically processed during the initialization of the Python interpreter, allowing for the execution of arbitrary code whenever Python is invoked.[1]

Path configuration files are designed to extend Python’s module search paths through the use of import statements. If a `.pth` file is placed in Python's `site-packages` or `dist-packages` directories, any lines beginning with `import` will be executed automatically on Python invocation.[2] Similarly, if `sitecustomize.py` or `usercustomize.py` is present in the Python path, these files will be imported during interpreter startup, and any code they contain will be executed.[3]

Adversaries may abuse these mechanisms to establish persistence on systems where Python is widely used (e.g., for automation or scripting in production environments).

View the same entry on attack.mitre.org (MITRE-hosted reference; in-page links above use the Glexia ATT&CK library.)

Glexia analysis

How security teams should use this page

Treat this object as behavior context, not an attribution claim. Validate the related groups, software, data sources, and mitigations against official ATT&CK relationships and your own telemetry before making control-coverage decisions.

ATT&CK relationship table

Related techniques

This mirrors the MITRE pattern of making group, software, campaign, and technique relationships scannable. Relationship notes come from mirrored ATT&CK relationship text when available.

1 rows
DomainIDNameRelationship / procedure
EnterpriseT1546Event Triggered ExecutionThis object subtechnique of Event Triggered Execution.
Associated objects

Groups, software, and campaigns

MalwareEnterprise

S9041: TeamPCP Cloud Stealer

The TeamPCP Cloud Stealer is a comprehensive filesystem credential stealer that can harvest, encrypt, and exfiltrate credentials from over 50 sensitive file paths across CI/CD, cloud, developer tooling, and container environments. The TeamPCP Cloud Stealer was the primary payload used by TeamPCP in March 2026 during early stages of a cascading supply chain campaign targeting CI/CD workflows.[1][2][3][4][5][6][7][8]

ContainersLinuxmacOS
MalwareEnterprise

S9043: Mini Shai-Hulud

Mini Shai-Hulud is a credential stealer and self-replicating supply chain worm, derived from Shai-Hulud, that has been used by TeamPCP to target Continuous Integration and Continuous Delivery/Deployment (CI/CD) workflows since at least 2026. Mini Shai-Hulud can compromise credentials across multiple cloud, container, and AI configuration file paths and can use stolen npm and GitHub OIDC tokens to spread to other packages maintained by the compromised user. Mini Shai-Hulud also has a targeted wiper component and has used multiple C2 and data exfiltration mechanisms.[1][2][3][4][5][6]

ContainersIaaSLinux
Relationship explorer

All related ATT&CK context

Change history

Object version and sync metadata

The fields below describe the current mirrored snapshot. When Glexia retains multiple ATT&CK source imports, you can open the table to compare the same object across releases (hashes and MITRE timestamps). For MITRE’s own release notes and roadmap, see ATT&CK resources — Updates.

ATT&CK release
19.2
Object version
1.0
Created
Modified
Raw hash
81d4b0989125c8cb...
Imported snapshots across ATT&CK releases(2)
ReleaseBundle importedObject versionModifiedStatusRaw hash
19.21.0Current bundle81d4b0989125…
19.11.0Older bundle81d4b0989125…
Raw source

Mirrored ATT&CK source object

The raw object is retained through the mirrored ATT&CK source bundle and object hash. The raw endpoint returns the exact object from the mirrored bundle when available.

Source references

External references and citations

MITRE external references are preserved separately from Glexia analysis so citations remain traceable to their original source records.

  1. [1]
    Volexity GlobalProtect CVE 2024

    Volexity Threat Research. (2024, April 12). Zero-Day Exploitation of Unauthenticated Remote Code Execution Vulnerability in GlobalProtect (CVE-2024-3400). Retrieved May 22, 2025.

    Open source URL
  2. [2]
    DFIR Python Persistence 2025

    Stephan Berger. (2025, January 14). Analysis of Python's .pth files as a persistence mechanism. Retrieved May 22, 2025.

    Open source URL
  3. [3]
    Python Site Configuration Hook

    Python. (n.d.). site — Site-specific configuration hook. Retrieved May 22, 2025.

    Open source URL
  4. [4]
    mitre-attackT1546.018
    Open source URL
Source and licensing

Source: MITRE ATT&CK®. © 2026 The MITRE Corporation. This work is reproduced and distributed with the permission of The MITRE Corporation. MITRE ATT&CK and ATT&CK are registered trademarks of The MITRE Corporation. Glexia is not affiliated with or endorsed by MITRE.